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Thursday, January 21, 2010

Type 2 Diabetes

Type 2 Diabetes Mellitus
Also known as:
• Adult onset Diabetes Mellitus
• Non-Insulin Dependent Diabetes Mellitus
• Ketosis Resistant Diabetes Mellitus

Type 2 Diabetes Mellitus is a adult onset, and non-insulin dependent. There are 2 main problems related to insulin in type 2 diabetes, first one is “insulin resistance “ (insulin do not bind with the special receptor on cell surface) and impaired insulin secretion (insulin secreting glands release irregular amount of insulin). Exact mechanism that leads to this problem s is unknown, but there are some factors that can predispose to type 2 Diabetes Mellitus in the family. However, despite of the impaired insulin secretion, there is enough insulin present in the blood to prevent the “lipolysis” (breakdown of fat) and the accompanying production of “ketone bodies” (by product of fatty acids). Therefore, Diabetic Ketoacidos does not typically occur in type 2 Diabetes Mellitus. Uncontrolled type 2 Diabetes Mellitus may lead to other acute problems including Hyperglycemic, Hyperosmolar Non-ketotic syndrome (HHNS).


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